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. 2020 Aug 29;28(3):279–293. doi: 10.1038/s41417-020-00218-z

Fig. 7. Knockdown of hsa_circ_102002 reduced lung metastasis of PTC in vivo.

Fig. 7

a Relative luciferase activity in sh-NC or sh-circ_102002 TPC-1 cells prior to the cells being injected into mice. b Tumor metastasis progression was measured by in vivo luciferase imaging at days 21 after intravenous injection of sh-NC or sh-circ_102002 TPC-1 cells. c Representative images and H&E staining analysis of lungs dissected from mice with intravenous injection of sh-NC or sh-circ_102002 TPC-1 cells. Quantification of the lung tumor nodules was shown as histograms. d IHC staining of HAS2, p-FAK, p-Akt, E-cadherin, and N-cadherin in the lungs dissected from mice with intravenous injection of sh-NC or sh-circ_102002 TPC-1 cells.