Table 4.
Significance* of difference in mean marker values and direction of dysregulation in the more severe group in intergroup comparison for top 5 RF importanta biomarkers.
| RF | S2 vs. S1 | S1 vs. HCs | S2 vs. HCs | PTSD cases vs. HCs |
|---|---|---|---|---|
| # markers retained in RF | 10 | 23 | 37 | 48 |
| hsa.miR.93.3p | <0.001 (4) ▼ | <0.001 (1) ▼ | ||
| cg01882498 | 0.003 (1) ▼ | |||
| cg01208318 | <0.001 (4) ▼ | <0.001 (2) ▼ | ||
| cg20720918 | <0.001 (1) ▼ | <0.001 (3) ▼ | ||
| cg13034868 | 0.001 (1) ▼ | |||
| hsa.miR.106b.3p | <0.001 (2) ▼ | <0.001 (4) ▼ | ||
| lactate | <0.001 (3) ▲ | |||
| cg23594345 | <0.001 (2) ▼ | <0.001 (5) ▼ | ||
| cg15687973 | 0.001 (3) ▼ | |||
| cg18171204 | 0.594 (2) | |||
| hsa.miR.127.3p | <0.001 (5) ▼ | |||
| cg03267026 | 0.002 (5) ▲ | |||
| cg06751007 | 0.211 (3) | |||
| eosino | 0.106 (4) | |||
| APOF.SGV | 0.023 (5) |
▼ = for significant markers, downregulated in more severe group based on comparison of mean values.
▲ = for significant markers, upregulated in more severe group based on comparison of mean values.
*FWER, Bonferroni corrected p < 0.0025, p-value bolded.
a() = importance rank in RF.