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. 2021 Apr 20;11:8554. doi: 10.1038/s41598-021-87975-5

Table 5.

Multivariate regression analysis of factors associated with HCV infection.

OR 95% CI Adjusted p-value
Anti-HCV seropositivity among all subjects
Age 0.98 0.92–1.04 0.543
AST 1.03 0.94–1.12 0.520
ALT 1.00 0.96–1.05 0.996
FIB-4 1.02 0.45–2.33 0.955
IDU (yes vs no) 18.45 1.41–241.76 0.026
Anti-HBc (positive vs negative) 0.00 0.00- 1.000
HBV DNA (positive vs negative) 0.31 0.11–0.86 0.024
Anti-HDV (positive vs negative) 12.25 4.85–30.93 1.1 × 10–7
HCV viremia among anti-HCV (+) subjects
AST 1.03 0.97–1.09 0.363
ALT 1.05 1.02–1.08 0.002
BMI 0.89 0.83–0.97 0.004
FIB-4 0.66 0.43–1.01 0.056
HBsAg (positive vs negative) 0.42 0.21–0.85 0.016
HCV viremia among treatment naïve anti-HCV (+) subjects
AST 1.02 0.95–1.10 0.605
ALT 1.04 1.00–1.08 0.060
BMI 0.86 0.79–0.94 0.001
FIB-4 0.84 0.44–1.60 0.589
HBsAg (positive vs negative) 0.27 0.13–0.58 6.9 × 10–4

HCV hepatitis C virus; anti-HCV hepatitis C antibody; AST aspartate aminotransferase; ALT alanine aminotransferase; BMI body mass index; FIB-4 Fibrosis-4 index; IDU injecting drug users; HBsAg hepatitis B surface antigen; anti-HBc hepatitis B core antibody; HBV DNA hepatitis B virus deoxyribonucleic acid; anti-HDV hepatitis D antibody.