Figure 3.

Cytochleograms comparing the mean outer hair cell loss across the cochlea spiral at 24 months of age in mice from the group that had rapamycin added to diet at 14 months of age (red line) vs. the control diet group without rapamycin added to diet (blue line). Apical cochlea is to the left and base to the right, the transition from apical turn to basal turn is ~1.75 mm from the apex and the transition from basal turn to the hook is at ~3.9 mm from apex. There is large loss of outer hair cells in the apical third of the cochlea in both groups and minimal loss in the remaining cochlea (including hook) in both groups.