TABLE 1.
Demographic and Clinical Characteristics of Patients With Oropharyngeal Cancer Who Survived at Least 5 Years After Diagnosis
| Characteristic | No. of Patients (%) |
|---|---|
| Age at diagnosis, median (IQR), y | 60 (55–68) |
| Radiation dose, median (IQR), Gy | 70 (66–70.5) |
| Sex | |
| Male | 1407 (82.8) |
| Female | 292 (17.2) |
| Period of diagnosis | |
| 1980–1989 | 133 (7.8) |
| 1990–1999 | 311 (18.3) |
| 2000–2013 | 1255 (73.9) |
| Smoking status | |
| Never | 744 (44.2) |
| Former | 571 (33.9) |
| Current | 370 (22.0) |
| Missing | 14 |
| Smoking, pack-years | |
| ≤10 | 956 (58.4) |
| >10 | 680 (41.6) |
| Missing | 63 |
| Site | |
| Tonsil | 773 (45.5) |
| Base of tongue | 821 (48.3) |
| Other | 105 (6.2) |
| HPV status | |
| Negative | 48 (10.1) |
| Positive | 429 (89.9) |
| Missing | 1222 |
| T category | |
| T1 | 523 (30.8) |
| T2 | 639 (37.6) |
| T3 | 353 (20.8) |
| T4 | 183 (10.8) |
| Missing | 1 |
| N category (AJCC 7th ed.) | |
| N0 | 218 (12.9) |
| N1 | 330 (19.4) |
| N2 | 1045 (61.5) |
| N3 | 105 (6.2) |
| Missing | 1 |
| Neck dissection | |
| No | 1306 (76.9) |
| Yes | 393 (23.1) |
| IMRT | |
| No | 621 (36.6) |
| Yes | 1078 (63.4) |
| Fractionation | |
| Conventional | 1164 (68.7) |
| Concomitant boost | 456 (26.9) |
| Other | 75 (4.4) |
| Missing | 4 |
| Radiation dose, Gy | |
| >70 | 440 (26.0) |
| >66–70 | 622 (36.7) |
| ≤66 | 633 (37.3) |
| Missing | 4 |
| Chemotherapy | |
| None | 726 (42.7) |
| Adjuvant only | 266 (15.7) |
| Concurrent only | 485 (28.5) |
| Both | 222 (13.1) |
| Recurrencea | |
| None | 1614 (95.0) |
| Local | 53 (3.1) |
| Regional | 9 (0.5) |
| Distant | 35 (2.1) |
| Second primary tumor | |
| No | 1408 (84.5) |
| Yes | 258 (15.5) |
| Missing | 33 |
Abbreviations: AJCC, American Joint Committee on Cancer; HPV, human papillomavirus; IMRT, intensity-modulated radiation therapy; IQR, interquartile range.
a
Groups not mutually exclusive.