Table 1.
Select examples of successful pharmacovigilance studies in which ADR and RWD database studies played a prominent role
| Drug(s) | Effect(s) | Source(s) | Citation |
|---|---|---|---|
| Acetaminophen | Liver injury | HER | 15 |
| Agomelatine | Liver injury | Lit review | 16 |
| Gabapentin, pregabalin | Liver injury, hematological disorders | ADR database | 17 |
| Apixaban | Liver injury | Case report, ADR database | 18 |
| Ketoconazole | Liver injury | Lit review, ADR database | 19 |
| Methadone | Arrhythmia | Lit review, ADR database | 20 |
| Ranolazine | Seizure | Sentinel | 21 |
| Levetiracetam, phenytoin | Angioedema | OHDSI | 22 |
| Citalopram | Arrhythmia | EHR | 23 |
| Hydroxyzine | Arrhythmia | Lit review, ADR database | 24 |
ADR, adverse drug reaction; EHR, electronic health record; OHDSI, Open Health Data Science Informatics; RWD, real‐world data.