Table 3 -.
Hazard Ratios for CVD events by CAC score group
| CAC Score | CVD Event Type and All-cause Mortality, HR (95% CI) | ||||
|---|---|---|---|---|---|
| All CVD | Hard CVD | All CHD | Hard CHD | All-cause mortality | |
| CAC 0 as reference group | |||||
| Model 1, unadjusted HRs | |||||
| 0 | REF | REF | REF | REF | REF |
| 1-399 | 3.31 (2.84 - 3.85) | 3.00 (2.52 - 3.57) | 4.18 (3.41 - 5.11) | 3.70 (2.94 - 4.65) | 2.41 (2.15 - 2.71) |
| 400-999 | 6.88 (5.59 - 8.48) | 5.68 (4.45 - 7.24) | 9.76 (7.55 - 12.62) | 7.69 (5.68 - 10.41) | 4.23 (3.56 - 5.02) |
| ≥ 1000 | 10.95 (8.76 - 13.68) | 7.78 (5.92 - 10.21) | 15.53 (11.83 - 20.37) | 11.72 (8.48 - 16.21) | 6.65 (5.53 - 7.99) |
| Model 2, fully adjusted * HRs | |||||
| 0 | REF | REF | REF | REF | REF |
| 1-399 | 2.06 (1.74 - 2.43) | 1.80 (1.49 - 2.19) | 2.77 (2.22 - 3.45) | 2.24 (1.74 - 2.88) | 1.20 (1.05 - 1.37) |
| 400-999 | 3.12 (2.46 - 3.97) | 2.51 (1.90 - 3.32) | 4.92 (3.66 - 6.61) | 3.42 (2.41 - 4.85) | 1.48 (1.22 - 1.80) |
| ≥ 1000 | 4.71 (3.63 - 6.11) | 3.18 (2.31 - 4.36) | 7.57 (5.50 - 10.42) | 4.86 (3.32 - 7.11) | 1.94 (1.57 - 2.41) |
| CAC 400-999 as reference group | |||||
| Model 1, unadjusted HRs | |||||
| 400-999 | REF | REF | REF | REF | REF |
| ≥ 1000 | 1.57 (1.23 - 2.00) | 1.36 (1.00 - 1.84) | 1.57 (1.19 - 2.08) | 1.51 (1.07 - 2.14) | 1.57 (1.27 - 1.95) |
| Model 2, fully adjusted * HRs | |||||
| 400-999 | REF | REF | REF | REF | REF |
| ≥ 1000 | 1.65 (1.25 - 2.16) | 1.33 (0.94 - 1.86) | 1.66 (1.22 - 2.25) | 1.51 (1.03 - 2.23) | 1.34 (1.05 - 1.71) |
*
Adjusted on age, sex, race/ethnicity, obesity, hypertension, total cholesterol, HDL-cholesterol, triglycerides, smoking, diabetes, family history of MI, anti-hypertensive medications, cholesterol medications