Predicted depressive symptoms as a function of person-centered CRP and cancer-related stress (panel a), general stress perceptions (panel b), and childhood stress (panel c). Elevated CRP was associated with increased depressive symptoms only among women who reported high cancer related stress and high general stress perceptions. Predicted depressive symptom scores were adjusted for age, BMI, race, surgery, cancer stage and receipt of chemotherapy, radiation therapy and endocrine therapy. Shaded areas depict confidence intervals of simple slopes. The asterisk symbols (*) index statistically significant simple slopes (p < .05).