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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Mar 18;222:108674. doi: 10.1016/j.drugalcdep.2021.108674

Table 3.

Multivariable logistic regression analyses examining factors associated with opioid pain medication misuse in the past 12 months among transgender adults in Massachusetts and Rhode Island (N = 562).

Block 1: Demographics Block 2: Demographics, Victimization, Mental Health, Social Support & Substance Misuse
Multivariable Multivariable
aOR 95% CI P-Value aOR 95% CI P-Value
DEMOGRAPHICS – CURRENT
Young Adult
 No (30+) 1.00 ---- ---- 1.00 ---- ----
 Yes (18–29) 0.91 0.48–1.76 0.78 0.68 0.28–1.67 0.40
Race/ethnicity
 White (non-Hispanic) 1.00 ---- ---- 1.00 ---- ----
 Racial/ethnic minority 0.84 0.36–1.92 0.68 0.45 0.13–1.55 0.20
Gender Identity
 Trans woman 2.08 0.95–4.56 0.07 3.22 1.05–9.93 0.04
 Trans man 1.65 0.74–3.67 0.22 2.90 0.94–8.91 0.06
 Non-binary 1.00 ---- ---- 1.00 ---- ----
Living with HIV
 No 1.00 ---- ---- 1.00 ---- ----
 Yes 5.74 1.41–23.40 0.01 9.01 1.19–68.18 0.03
Health Insurance
 No insurance 3.04 0.63–14.76 0.17 2.77 0.36–21.38 0.33
 Public insurance 3.12 1.62–6.01 0.001 2.14 0.87–5.29 0.10
 Private insurance 1.00 ---- ---- 1.00 ---- ----
VICTIMIZATION
Physical or Sexual Abuse as a Child
 No 1.00 ---- ----
 Yes 0.78 0.29–2.07 0.61
Physical or Sexual Abuse in Adulthood
 No 1.00 ---- ----
 Yes 1.20 0.43–3.31 0.73
Everyday Transgender-Related Discrimination - Lifetime
 Continuous 1.01 0.97–1.06 0.61
Experiencing Stigma in a Healthcare Setting - Past 3 Years
 No 1.00 ---- ----
 Yes 5.51 1.84–16.54 0.002
Harassed or Attacked in a Healthcare Setting - Past 3 Years
 No 1.00 ---- ----
 Yes 0.45 0.11–1.94 0.28
MENTAL HEALTH & SELF-HARM
Internalized Transphobia - Current
 Absent 1.00 ---- ----
 Neither fully absent nor fully present 1.77 0.61–5.14 0.29
 Present 1.43 0.52–3.96 0.49
Depression - Current
 No 1.00 ---- ----
 Yes 0.43 0.10–1.78 0.24
Anxiety - Current
 No 1.00 ---- ----
 Yes 1.22 0.33–4.52 0.77
Post-Traumatic Stress Disorder - Current
 No 1.00 ---- ----
 Yes 1.41 0.50–3.95 0.52
NSSI - Lifetime
 No 1.00 ---- ----
 Yes 0.73 0.25–2.13 0.56
Attempted Suicide - Lifetime
 No 1.00 ---- ----
 Yes 0.69 0.27–1.78 0.45
SOCIAL SUPPORT - CURRENT
Social Connectedness
 Suboptimal 0.33 0.14–0.80 0.01
 Optimal 1.00 ---- ----
Family Support of Gender Identity/Expression
 Supportive ---- ---- ----
 Somewhat supportive ---- ---- ----
 Not supportive ---- ---- ----
SUBSTANCE MISUSE - PAST 12 MONTHS
Number of Other Substances
 Continuous 2.74 1.94–3.89 <.0001

OR=Odds Ratio; aOR= Adjusted Odds Ratio; NSSI = non-suicidal self-injury; bolded values = significant at p<0.05.

**

Not inclusive of opioid pain medications

Note. Blocked multivariable regression modeling was used. Demographics were entered into the first block. Variables significant at p<0.25 were entered into the final multivariable model.Both models adjusted for age and race/ethnicity.