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Aberrant auto-antibody glycosylation observed in autoimmune diseases
| Glycosylation | RA | AAV | FNAIT | |
|---|---|---|---|---|
| Glycosylation of autoantibody Fc region | Agalactosylation | ACPA IgG1↑ [112] | ANCA IgG1↑ [135] | |
| Galactosylation | ANCA IgG1↓ [135] | HPA-1a specific IgG1↑ [138] | ||
| Sialylation | ACPA IgG1↓ [112] | ANCA IgG1↓ [135] | HPA-1a specific IgG1↑ [138] | |
| Fucosylation | ACPA IgG1↑ [6, 112] | HPA-1a specific IgG1↓ [35, 138, 139] | ||
| Bisection | ANCA IgG1↓ [135] |
