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. 2021 Apr 20;11:8531. doi: 10.1038/s41598-021-88050-9

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Modified Raynaud scan of preserved vasoreactivity case. (A) High signal intensity in left periventricular white matter on the diffusion-weighted image. (B) Scan for both hands and standard source. (C) Congested right fingertips in resting state. Activity % of the total injected dose means the percentage of total blood. (D) Preserved vasoreactivity under thermal stress. The amount of blood in the right hand became equal to the amount in the left hand, and the pattern was stable during the scan. The shaded area in (C,D) represents the reference range obtained from 10 normal volunteers. R: right; L: left; Std: standard.