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. 2021 Apr 20;4:486. doi: 10.1038/s42003-021-02011-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a gMFI values obtained by C19BA (left) and OD values obtained by ELISA (right) corresponding to levels of IgG against RBD, S1, and N for the indicated cohorts. b Representative dot plots obtained by C19BA showing IgG levels for COVID negative (n = 18), mild/moderate COVID (n = 18), and severe COVID serums (n = 16) obtained from PCR+ individuals at the time of hospital admission. Statistical analyses were performed using two-way ANOVA. Asterisks represent p values (****p < 0.0001, *p < 0.05). Horizontal lines represent median values.