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. 2021 Apr 7;12:645170. doi: 10.3389/fimmu.2021.645170

Figure 2.

Figure 2

Forest plot for the efficacy of anti-programmed death-1/programmed death-ligand 1 agents in patients with different human papillomavirus status. (A) Objective response rate (ORR) of the included studies stratified by the type of immune checkpoint blockade. Squares indicate adjusted effect size (odds ratio [OR]). Horizontal lines represent 95% confidence interval (95%CI). Diamonds represent the pooled ORs; (B) Disease control rate (DCR) of the included studies. Squares indicate adjusted effect size (odds ratio [OR]). Horizontal lines represent 95%CI. Diamonds represent the pooled ORs. Pooled ORs were calculated using the fixed-effect model. PD-1, Programmed death 1; PD-L1, Programmed death-ligand 1; HPV, human papillomavirus; +, positive; -, negative.