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. 2021 Apr 7;11:567648. doi: 10.3389/fonc.2021.567648

Table 2.

Critical predictors obtained by univariate logistic regression analysis.

Features All Patients, n(%) ALN ALN P value
Negative, n (%) Positive, n (%)
Age(y) 47.00(23.00,88.00) 47.00(23.00,86.00) 46.00(25.00,88.00) 0.130
Quantity <0.001
Single 437(83.56) 229(43.79) 208(39.77)
Multiple 86(16.44) 27(5.16) 59(11.28)
Shape 0.005
Oval, round 62(11.85) 41(7.84) 21(4.01)
Irregular 461(88.15) 215(41.11) 246(47.04)
Orientation <0.001
Parallel 333(63.67) 195(37.29) 138(26.38)
Not parallel 190(36.33) 61(11.66) 129(24.67)
Margin contour 0.044
Smooth 36(6.88) 23(4.40) 13(2.48)
Lobulate 84(16.06) 44(8.41) 40(7.65)
Angular, Spiculate 403(77.06) 189(36.14) 214(40.92)
Margin 0.849
Circumscribed 40(7.65) 19(3.63) 21(4.02)
Not circumscribed 483(92.35) 237(45.32) 246(47.03)
Boundary 0.828
Abrupt interface 261(49.90) 129(24.67) 132(25.23)
Echogenic halo 262(50.10) 127(24.28) 135(25.82)
Main posterior echo 0.002
Enhancement 9(1.72) 7(1.34) 2(0.38)
Indifferent 294(56.21) 157(30.01) 137(26.20)
Shadowing 220(42.07) 92(17.59) 128(24.48)
Microcalcification <0.001
Absent 228(43.59) 134(25.62) 94(17.97)
Preserved 295(56.41) 122(23.33) 173(33.08)
Echogenicity pattern 0.030
Other echo 17(3.25) 13(2.49) 4(0.76)
Hypoechoic 506(96.75) 243(46.46) 263(50.29)
CDFI <0.001
Adler 0,1 192(36.71) 122(23.32) 70(13.39)
Adler 2,3 331(63.29) 134(25.62) 197(37.67)
US tumour size(mm) 22,00(5.00,140.00) 19.00(5.00,77.00) 27.00(7.00,140.00) <0.001
ER 0.668
Negative 171(32.70) 86(16.45) 85(16.25)
Positive 352(67.30) 170(32.50) 182(34.80)
PR 0.211
Negative 229(43.79) 105(20.08) 124(23.71)
Positive 294(56.21) 151(28.87) 143(27.34)
HER-2 0.002
Negative 379(72.47) 205(39.20) 174(33.27)
Positive 144(27.53) 51(9.75) 93(17.78)
Ki-67 0.121
Negative 159(30.40) 86(16.44) 73(13.96)
Positive 364(69.60) 170(32.50) 194(37.10)
US of lymph node <0.001
No lymph nodes found 214(40.92) 165(31.55) 49(9.37)
Lymph nodes found 309(59.08) 91(17.40) 218(41.68)
Aspect ratio <0.001
No lymph nodes found 220(42.07) 165(31.55) 55(10.52)
Aspect ratio≥2 111(21.22) 53(10.13) 58(11.09)
Aspect ratio<2 192(36.71) 38(7.27) 154(29.44)
Cortical thickness <0.001
No lymph nodes found 213(40.73) 165(31.55) 48(9.18)
Thickness<3 mm 118(22.56) 82(15.68) 36(6.88)
Symmetric thickness≥3 mm 19(3.63) 2(0.38) 17(3.25)
Asymmetric thickness≥3 mm 173(33.08) 3(1.34) 166(31.74)
Central hilum <0.001
No lymph nodes found 207(39.58) 162(30.98) 45(8.60)
Preserved 147(28.11) 87(16.63) 60(11.48)
Partially absent 70(13.38) 5(0.96) 65(12.42)
Completely absent 99(18.93) 2(0.38) 97(18.55)