FIGURE 5.

MI increases the abundance of ^MetRS*MSC exosomal proteins in the heart. ^MetRS*MSC-Exos were injected into the tail vein of mice 24 h after MI induction or Sham surgery (n = 3 per group). Animals were euthanized 24 h after exosome administration, and protein extracts were prepared from the left ventricle; then, the ANL-labeled ^MetRS*MSC exosomal proteins were isolated via click-catalyzed alkyne-agarose capture and identified via LC-MS. (A) Heat map of all identified ^MetRS*MSC exosomal proteins. (B) Heat map of ^MetRS*MSC exosomal proteins that were differentially expressed in MI and Sham hearts.