. 2021 Apr 7;8:654624. doi: 10.3389/fnut.2021.654624

Table 5.

Fortified SFY impact on relative organs weights and plasma biochemical profile of treated rats.

Parameters	Units	G1	G2	G3	G4	G5	G6
Relative weight gain and organs weights
Weight gain		13.51 ± 3.73^b	8.81 ± 2.32^c	14.42 ± 4.03^b	19.58 ± 1.56^a	15.79 ± 2.86^ab	14.37 ± 2.07^b
Liver		3.53 ± 027^a	3.79 ± 0.55^a	4.23 ± 1.39^a	3.52 ± 0.32^a	3.71 ± 0.48^a	3.39 ± 0.37^a
Kidney		0.63 ± 0.09^a	0.72 ± 0.23^a	0.84 ± 0.08^a	0.74 ± 0.08^a	0.76 ± 0.16^a	0.74 ± 0.06^a
Spleen		0.52 ± 0.16^a	0.70 ± 0.20^a	0.88 ± 0.44^a	0.73 ± 0.11^a	0.83 ± 0.43^a	0.66 ± 0.14^a
Heart		0.46 ± 0.01^a	0.46 ± 0.14^a	0.40 ± 0.04^a	0.38 ± 0.01^a	0.42 ± 0.03^a	0.36 ± 0.02^a
Lungs		0.77 ± 0.03^a	0.84 ± 0.28^a	0.86 ± 0.14^a	0.78 ± 0.02^a	0.84 ± 0.33^a	0.82 ± 0.11^a
Plasma biochemical profile
Glucose	mg dL⁻¹	203.25 ± 30.70^a	169.00 ± 31.60^a	187.75 ± 46.89^a	185.00 ± 38.56^a	192.50 ± 31.09^a	169.75 ± 20.96^a
Plasma lipid profile
T.Ch.	mg dL⁻¹	90.50 ± 7.89^bc	94.00 ± 12.19^ab	74.75 ± 7.93^c	88.25 ± 6.18^bc	89.75 ± 5.73^bc	108.75 ± 16.60^a
TG	mg dL⁻¹	182.25 ± 10.62^a	105.50 ± 9.88^b	76.50 ± 13.07^b	107.00 ± 16.43^b	99.50 ± 13.10^b	128.75 ± 75.07^b
HDL	mg dL⁻¹	32.00 ± 4.08^c	45.00 ± 5.35^ab	35.50 ± 7.85^bc	42.25 ± 8.05^abc	40.00 ± 3.36^bc	51.00 ± 9.76^a
LDL	mg/dL⁻¹	22.75 ± 3.30^b	29.25 ± 10.04^ab	27.75 ± 7.63^ab	28.25 ± 3.59^ab	29.25 ± 4.03^ab	33.75 ± 7.41^a
Liver function
AST	IU L⁻¹	195.5 ± 051.00^a	214.50 ± 48.23^a	176.75 ± 15.10^a	189.75 ± 31.60^a	170.50 ± 17.21^a	173.25 ± 26.98^a
ALT	IU L⁻¹	27.75 ± 5.12^b	41.75 ± 11.08^a	30.75 ± 3.20^b	42.00 ± 6.21^a	28.503.10^b	29.50 ± 2.08^b
ALP	IU L⁻¹	288.75 ± 23.94^a	287.50 ± 24.44^a	241.50 ± 27.04^a	262.25 ± 34.09^a	293.5 ± 42.16^a	264.25 ± 41.32^a
T. Bilirubin	g dL⁻¹	0.2175 ± 0.10^a	0.2325 ± 0.02^a	0.2075 ± 0.03^a	0.2275 ± 0.02^a	0.2850 ± 0.11^a	0.2350 ± 0.07^a
Kidney function
Urea	mg dL⁻¹	27.75 ± 3.59^b	37.00 ± 4.96^a	34.00 ± 3.36^a	26.50 ± 5.06^b	27.00 ± 1.82^b	27.75 ± 1.70^b
Creatinine	μmol L⁻¹	0.985 ± 0.08^a	0.970 ± 0.10^a	0.960 ± 0.07^a	0.983 ± 0.16^a	0.975 ± 0.17^a	0.983 ± 0.10^a

Data represented are means of relative weights (g) (n = 5) ±SD. Means in the same row followed by different letters are significantly different (p ≤ 0.05). A, G1 Negative control; B, G2 Positive control Group; C, G3 Fed SFY fortified with free Fe + ascorbic acid; D, G4 Fed SFY fortified with free Fe + FA + ascorbic acid; E, G5 Fed SFY fortified with Fe@ BSA-NPs + ascorbic acid; F, G6 Fed SFY fortified with Fe + FA@ BSA-NPs + ascorbic acid. BSA-NPs, Bovine Serum Albumin nanoparticles; FA, Folic Acid; T.Ch, Total cholesterol; TG, Triglycerides; HDL, High-density lipoprotein; LDL, Low-density lipoprotein; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; ALP, Alkaline phosphatase.