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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Expert Opin Drug Discov. 2020 Dec 1;16(5):497–511. doi: 10.1080/17460441.2021.1851188

Figure 2.

Figure 2.

A) General CYP450 cycle and hormones conversion catalyzed by aromatase (AR) and CYP17A1 [77]. B) The three oxidation steps catalyzed by AR. C) 17α-hydroxylation and 17α-20-lyase reactions of pregnenolone as performed by CYP17A1.