Table 1.
Clinicopathological characteristics of the cohort.
| Characteristic | All(n = 36,813) | Germline mutation carriers(n = 131) | P |
|---|---|---|---|
| Age, years | |||
| median [IQR] | 62.00 [54.00, 69.00] | 62.00 [54.75, 68.25] | 0.76 |
| Sex, n (%) | 0.346 | ||
| Male | 18295 (49.7) | 73 (55.7) | |
| Female | 15525 (42.2) | 50 (38.2) | |
| Unknown | 2993 (8.1) | 8 (6.1) | |
| Histology, n (%) | 0.923 | ||
| Lung adenocarcinoma | 24977 (67.8) | 92 (70.2) | |
| Lung squamous carcinoma | 2131 (5.8) | 7 (5.3) | |
| Small cell lung carcinoma | 9262 (25.2) | 31 (23.7) | |
| Others | 443 (1.2) | 1 (0.8) | |
| Clinical Stage, n (%) | 0.029 | ||
| I-IIIA | 8200 (22.3) | 33 (25.2) | |
| IIIB-IV | 23778 (64.6) | 91 (69.5) | |
| Unknown | 4835 (13.1) | 7 (5.3) |