TABLE 1.

Cellular processes regulated by vasopressin in collecting duct principal cells

Vasopressin Actions	References	Fig. 2 Cluster
Accelerates Aqp2 gene transcription	Hasler et al., 2009; Sandoval et al., 2016	1
Mobilizes intracellular calcium	Star et al., 1988; Champigneulle et al., 1993; Chou et al., 2000	2
Reorganizes filamentous actin	Simon et al., 1993; Tamma et al., 2001; Chou et al., 2004; Loo et al., 2013	3
Depolymerizes filamentous actin	Simon et al., 1993; Tamma et al., 2001	4
Causes microtubule-dependent AQP2 redistribution	Sabolić et al., 1995	5
Accelerates exocytosis of AQP2-containing vesicles	Nielsen and Knepper, 1993; Nielsen et al., 1995; Nunes et al., 2008	6
Decreases AQP2 endocytosis	Nielsen and Knepper, 1993; Brown, 2003	7
Increases tight junction permeability	Mishler et al., 1990	8
Accelerates AQP2 translation	Khositseth et al., 2011; Sandoval et al., 2013	9
Increases AQP2 protein half-life	Nedvetsky et al., 2010; Sandoval et al., 2013	11
Slows rate of apoptosis	Miller et al., 2013	10
Slows rate of proliferation	Yamaguchi et al., 2003	–
Increases principal cell size	Ganote et al., 1968; Kirk et al., 1984; Nielsen et al., 1993; Chou et al., 2008	–