Table I.
Clinical and biological features of patients enrolled in the study, pooled according to medically assisted reproduction (MAR) stimulation and age.
|
Pool 1
(n = 10) |
Pool 2
(n = 10) |
Pool 3
(n = 9) |
Pool 4
(n = 9) |
|
|---|---|---|---|---|
| Age (years) | ≥36 (39.5 ± 2.63) | ≥36 (39 ± 2.67) | ≤35 (31.11 ± 2.37) | ≤35 (32.88 ± 2.62) |
| Stimulation protocol | r-hFSH | r-hFSH + r-hLH | r-hFSH | r-hFSH + r-hLH |
| BMI | 25.89 ± 1.10 | 20.03 ± 2.30 | 21.10 ± 1.50 | 22.20 ± 2.30 |
| LH (mIU/mL) | 3.35 ± 1.75 | 6.27 ± 4.38 | 3.80 ± 1.29 | 7.38 ± 1.68 |
| FSH (mIU/mL) | 7.32 ± 1.09 | 12.37 ± 5.41 | 6.67 ± 1.04 | 6.23 ± 1.42 |
| AMH | 2.79 ± 2.26 | 0.65 ± 0.28 | 4.42 ± 3.47 | 1.73 ± 1.18 |
| E2 a | 1167.75 ± 443.42 | 817.5 ± 437.98 | 884.25 ± 338.99 | 1881.25 ± 556.76 |
| P a | 0.78 ± 0.41 | 0. 77 ± 0.22 | 1.86 ± 0.25 | 0.71 ± 0.14 |
| Endometrial thickness (mm) | 8.00 ± 1.50 | 7.05 ± 2.00 | 10.75 ± 1.63 | 9.50 ± 0.75 |
| Follicles> 16 mm (n) | 7.25 ± 2.75 | 3.00 ± 1.82 | 7.25 ± 2.50 | 8.50 ± 4.35 |
| Oocyte retrieval (n) | 7.25 ± 0.41 | 2.50 ± 1.29 | 8.25 ± 1.25 | 8.50 ± 4.80 |
| Oocyte MII (n) | 6,30 ± 3.65 | 3,20 ± 1.47 | 8,60 ± 5.57 | 4.67 ± 2.28 |
| Fertilization rate (%) | 83% | 70% | 84% | 81% |
| β-HCG + (%) | 30% | 10% | 33% | 33% |
| AFC (n) | 5.3 ± 2.21 | 4.2 ± 1.3 | 10.83 ± 3.06 | 8 ± 2.78 |
r-hLH, recombinant human luteinizing hormone; r-hFSH, recombinant human follicle stimulation hormone; AMH, anti-Müllerian hormone; E2, estradiol; P: progesterone; MII, metaphase II; AFC, antral follicle count.
a
Measured at HGC administration.
The data were expressed as mean ± SD.