Figure 2. Participation to Prevalence Ratio (PPR) for Women.
The PPR is calculated by dividing the proportion of study patients who are women by the proportion of US cancer patients who are women, by cancer type. A PPR from 0.8 to 1.2 indicates adequate representation, a PPR less than 0.8 indicates underrepresentation, and a PPR greater than 1.2 indicates overrepresentation. Dotted blue lines indicate these boundaries; error bars, CIs. The number of trials included in the PPR by cancer type can be found in eTable 3 in the Supplement. Data for sex were missing for 14 postmarketing studies.