Table 1.
General information at each phase of data collection.
| Study component | Phase 1 (N=308) | Phase 2 (n=185) | Phase 3 (n=148) | |
| Design | Prospective | Prospective | Cross-sectional and retrospective | |
| Study visits | Routine clinical evaluation every 3 months; virological data collected every 6 months; fibrosis or serological data collected every 12 months | Routine clinical evaluation and data collection every 6 and 12 months for participants with F3/F4 and F0/F1/F2 fibrosis, respectivelya | Cross-sectional visit including comprehensive clinical evaluation on viral hepatitis and liver fibrosis; retrospective data collected since last visit in phase 1 or 2 | |
| Inclusion period | 2002-2003 | 2007-2008 | 2016-2018 | |
| Follow-up period | 2002-2006 | 2007-2011 | N/Ab | |
| Number of patients completing follow-up, n (%) | 275 (89.3) | 163 (88.1) | 147 (99.3) | |
| Number of deaths | ||||
|
|
Total | 3 | 8 | 31 |
|
|
Observed | 3 | 6c | 26c |
|
|
Updatedd | 0 | 2 | 5 |
| Follow-up time (years), median (IQR) | 3.0 (3.0-3.2) | 7.3 (3.1-8.0)e | 9.2 (3.4-14.6)e | |
aIn accordance with the European AIDS Clinical Society guidelines for the clinical management and treatment of chronic hepatitis B and C coinfection in adults with HIV [18].
bN/A: not applicable.
cIncludes deaths during time gaps in between phases.
dUsing linked data from a national death certificate registry (CépiDC).
eCumulated over previous phases—this statistic applies to all 308 patients regardless of the phase in which they discontinued participation.