Figure 1.

Schematic illustration of the fabrication of CD NAs from the coassembly of pure drug cocktails (cabazitaxel (CTX) and dasatinib (DAS)) for combination cancer therapy. The mixture of CTX/DAS in DMSO solvent is nonemissive, but upon aggregation, CD NAs emit intensive fluorescence, which can be used for intracellular nanoassembly trafficking. In addition, the CD NAs formulating dual drugs are suitable for intravenous injection. Once cellular uptake occurs, dual drugs with distinct modes of action can be released to exert their individual antitumor activities.