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. 2020 Aug 19;37(3):375–381. doi: 10.1093/bioinformatics/btaa735

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Effect of using FuSe. Several DETs changed their direction of regulation (up- or downregulated); here illustrated using two cases. (A) PPP1R14B-203 was upregulated with the standard method but, after the functional grouping-based analyses, it was shown to be downregulated for (i) ConDMSO versus APAP Ther and (ii) ConDMSO versus APAP Tox. (B) Similarly in the case of GBE1-205, for (i) ConUNTR versus APAP Tox and (ii) ConDMSO versus APAP Tox, it was exhibited as downregulated regulated after applying FuSe