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. 2021 Apr 14;13:17590914211003247. doi: 10.1177/17590914211003247

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© The Author(s) 2021

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — TET2 Silencing Decreased the TUG1 Level and Attenuated ORG 12 h/R 24 h Injury. A–C: TET2, TUG1, and miR-200a-3p expressions were detected by qRT-PCR after knockdown of TET2. D: A CCK-8 assay measured cell viabilities in ORG 12 h/R 24 h -induced SH-SY5Y and SK-N-SH cells after transfection with shNC or shTET2. E: IL-18 and IL-1β secretions were measured by ELISA in ORG 12 h/R 24 h -injured cells after knockdown of TET2. F: TET2, NLRP3, Caspase-1, and GSDMD-N expressions were determined by western blot in ORG 12 h/R 24 h -injured cells after knockdown of TET2. Four independent experiments were repeated, with three replicates each time, *p < 0.05, **p < 0.01, ***p < 0.001.