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. 2021 Mar 4;35(4):384–397. doi: 10.1177/0269881121992676

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution 4.0 Lficense (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Dose–response relationships for MEQ30 and HRS.

Dose-specific subjective effects of psilocybin for the psychometric instruments (a) MEQ30 and (b) HRS. Doses are given as microgram per kilogram body weight. Effects on the MEQ30 are presented as the percentage score of the maximum score. Effects on the HRS range from 0 to 4 (items in the questionnaire from 0 ‘Not at all’ to 4 ‘Extreme’). Circle colour indicates data from the same sample of participants (the same colour corresponds to statistically dependent data), circle size represents the weight of the data based on study variance (see Methods). Spiderplots present the estimated dose–responses for 100–600 μg/kg body weight on the MEQ30 and 100–400 μg/kg body weight on the HRS, corresponding to the range of doses that were included in the respective analyses.