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. Author manuscript; available in PMC: 2021 Apr 21.
Published in final edited form as: J Occup Environ Med. 2019 Dec;61(Suppl 12):S82–S89. doi: 10.1097/JOM.0000000000001691

Figure 3: Exposure to BghiP and HpCDD upregulate Let-7d and miR-103 levels.

Figure 3:

Primary human lung fibroblasts (HLFs) were treated with vehicle (DMSO), BghiP or HpCDD with the doses listed for 24 hours and total RNA was isolated. Let-7d (A), and miR-103 (B) were detected by RT-qPCR. At 1 µM BghiP treatment both Let-7d and miR-103 were upregulated but the induction was not significant. Let-7d and miR-103 levels were significantly induced with HpCDD exposure. The experiment was performed in 4 different HLF strains with similar results in all strains. Representative data from 1 strain presented as means ± standard error, ** = p < 0.01, One-way-ANOVA.