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Ultrastructural abnormalities of the ER and Golgi complex in a FFI fibroblast.A, electron micrograph of a FFI fibroblast. B, three-dimensional tomography reconstruction from virtual serial slices of the fibroblast shown in A. The dilated ER cisterna is colored green. The continuous distensions of trans-Golgi are in pale yellow/dark red, the cis-most cisterna of Golgi stack is light blue. COP I and clathrin-coated (red arrow) vesicles are indicated. Scale bars 200 nm.
