Equilibrium Ca2+titrations of CaM+FGF12B+NaV1.2CTDand CaM+FGF12A+NaV1.2CTD.A and B, equilibrium Ca2+ titrations of sites I and II (A), and sites III and IV (B) of CaM in CaM+NaV1.2CTD. Solid gray lines show reference Ca2+ titrations sites I and II (A) and sites III and IV (B) of CaM alone. C, E, equilibrium Ca2+ titrations of sites I and II of CaM in CaM+NaV1.2CTD (C, E, black), CaM+FGF12B+NaV1.2CTD (C, blue) and CaM+FGF12A+NaV1.2CTD (E, teal). D, F, equilibrium Ca2+ titrations of sites III and IV of CaM in CaM+NaV1.2CTD (D, F, black), CaM+FGF12B+NaV1.2CTD (D, red) and CaM+FGF12A+NaV1.2CTD (F, pink).