Changes in the hepatic pathophysiological conditions.
(A) Liver steatosis, stiffness, and Kupffer cells (KC) phagocytosis. (B) Biochemical markers of NASH and fibrosis. Esub n = 24, Wsub n = 21. Dark grey bars: Esub, light grey bars: Wsub (means ± SEMs). ∗p <0.05, ∗∗p <0.01, †p <0.05, ‡p <0.01, for baseline vs. 3 months. Within-group changes over time, between baseline and 3 months, for all variables were compared using paired t tests and independent t tests, or aANCOVA. TBARS, thiobarbituric acid-reactive substances; WFA+-M2BP, Wisteria floribunda agglutinin-positive human Mac-2 binding protein.