Figure 5. Increased Phagocytosis of S. aureus and E. coli in Atg7–/– Macrophages.
BMDMs from Atg7−/− and Atg7+/+ mice were infected for 30 min or 1 hr with pHrodo-labeled S. aureus or E. coli (MOI 10) and bacterial uptake was measured by flow cytometry. Representative overlaid histograms (A) and quantitative analyses (B) are shown. Data show the MFI relative to uninfected cells (mean ± SD), n = 3; *p < 0.05, **p < 0.001. See also Figure S4.