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. 2021 Apr 21;13:86. doi: 10.1186/s13195-021-00815-6

Table 3.

Diagnostic accuracy of plasma Nfl and t-tau in the discrimination of CJD

Plasma Nfl Plasma t-tau
CJD vs. Cutoff Sensitivity (%) Specificity (%) Cutoff Sensitivity (%) Specificity (%)
HC > 33 pg/mL 100 100 > 6.0 pg/mL 84 100
Non-CJD-Dem > 70 pg/mL 79 96 > 6.1 pg/mL 95 84
Non-CJD-neurodeg-Dem > 70 pg/mL 88 96 > 6.1 pg/mL 95 84

Sensitivity (in %), specificity (in %), and associated cutoff points (in pg/mL) for plasma Nfl and t-tau in the discrimination of CJD from HC, non-CJD-Dem, and non-CJD neurodeg-Dem