. Author manuscript; available in PMC: 2021 Apr 21.

Published in final edited form as: J Thromb Haemost. 2020 Feb 28;18(4):885–894. doi: 10.1111/jth.14744

Table 2.

Characteristics associated with normalized clot mass.

	All (N=86)		FXIII^Val/Val (N=40)		FXIII^Val/Leu (N=28)		FXIII^Leu/Leu (N=18)
	R	P	R	P	R	P	R	P
Clinical Characteristics
Age (years)	0.3602	0.0007	0.5244	0.0005	0.4113	0.0297	−0.1488	0.5557
FXIII Activity (%)	0.1126	0.3019	0.3506	0.0266	−0.1700	0.3872	0.2193	0.3819
Fibrinogen (g/L)	0.5267	<0.0001	0.5496	0.0002	0.6461	0.0002	−0.0298	0.9066
Clotting Tests
APTT (seconds)	0.0573	0.6004	0.0286	0.8610	0.1230	0.5330	−0.1755	0.4862
PT (seconds)	0.2248	0.0374	0.3127	0.0495	0.1017	0.6065	0.0614	0.8088
Thrombin Generation Parameters
Lag time (minutes)	0.3371	0.0015	0.4581	0.0030	0.2615	0.1790	−0.3436	0.1627
Time to Peak (minutes)	0.3036	0.0045	0.3159	0.0471	0.3595	0.0603	−0.1216	0.6306
Peak Thrombin (nM)	−0.0531	0.6272	−0.0297	0.8556	−0.1061	0.5911	0.0606	0.8113
ETP (nM*minute)	0.2495	0.0205	0.2597	0.1056	0.0252	0.8986	0.2486	0.3199

R, Spearman coefficients; APTT, activated partial thromboplastin time; PT, prothrombin time; ETP, endogenous thrombin potential