Figure 4.

Prediction performance of XPASS and related summary-level methods for height and BMI in the Chinese population

Compared methods include XPASS, XPASS₊, LDpred, and P+T. For LDpred and P+T, one of the five sets of GWAS summary statistics were used as training set: Chinese only, BBJ only, UKBB only, improved Chinese and UKBB summary statistics obtained by combining the two datasets using MTAG (MTAG-Chinese and MTAG-UKBB). Predictive R² for height and BMI are shown in (A) and (D). Panels in (A) and (D) represent the datasets used for training. Stratification ability of XPASS and LDpred for height (B) and BMI (E). Error bars represent ±1.96 of the standard error. The distributions of PRSs constructed by XPASS and LDpred for height (C) and BMI (F).