Table 5:

Duration of preoperative pause between last NOAC intake and the planned operation [14].

	Creatinine clearance (mL/min/1.73 m2)
	≥80	50–80	30–50	15–30
Operations with a low risk for bleeding
Dabigatran	≥24	≥36	≥48	Not indicated
Rivaroxaban	≥24	≥24	≥24	≥36
Edoxaban	≥24	≥24	≥24	≥36
Abixaban	≥24	≥24	≥24	≥36
Operations with a high risk for bleeding
Dabigatran	≥48	≥72	≥96	Not indicated
Rivaroxaban	≥48	≥48	≥48	≥48
Edoxaban	≥48	≥48	≥48	≥48
Abixaban	≥48	≥48	≥48	≥48