Table 1.

EC₅₀ Values for the 10 Hit MMV Pathogen Box Compounds, Amphotericin, and Miltefosine against L. amazonensis Axenic Amastigotes^a

compound	EC50 ± SE (nM)	compound	EC50 ± SE (nM)
MMV676412	51 ± 3.7	amphotericin B	53 ± 4.4
MMV676477	79 ± 8.4	buparvaquone	12 ± 1.1
MMV688372	160 ± 1.8	delamanid	31 ± 3.5
MMV652003	220 ± 50	auranofin	130 ± 2.5
MMV595321	240 ± 70	nitazoxanide	590 ± 100
MMV090930	520 ± 120	miltefosine	1200 ± 280

^aReference drugs included in the MMV Pathogen Box are labeled by their names, rather than the MMV number. Mean ${\text{EC}}_{50}^{72\mathrm{h}}$ values calculated from three biological repeats (in nM) ± SE of these three ${\text{EC}}_{50}^{72\mathrm{h}}$ values are shown.