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. 2021 Apr 7;10:595527. doi: 10.3389/fonc.2020.595527

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Copyright © 2021 Xie, Yang, Guo, Che, Xu, Sun, Liu, Ren, Liu, Yang, Ji and Tang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Improved OS in patients with high TMB. TMB was stratified with a binary cutoff of 2.565 (3rd quartile). Log-rank test was used to calculate P value. (A) OS curves of TMB-High and TMB-Low groups (P = 0.03). (B) OS curves of patients stratified by the combination of Gender and TMB. TMB-High Males (n=5), TMB-High Females (n=3), TMB-Low Males (n=12), TMB-Low Females (n=10) (P=0.005). The numbers in parentheses represented the number patients in each group.