Table 1.
Key references which compared colon ADR and AMR between water exchange and air insufflation colonoscopy
| Water exchange | Air insufflation | P | |
|---|---|---|---|
| Jia et al. [9] | 1653 cases | 1650 cases | |
| Overall BBPS (mean±SD): 7.3±1.6 | Overall BBPS: 7.0±2.3 | <0.001 | |
| Right colon BBPS: 2.3±0.7 | Right colon BBPS: 2.2±1.5 | <0.001 | |
| Overall ADR: 18.3% | Overall ADR: 13.4% | <0.001 | |
| Hsieh et al. [8] | 217 cases | 217 cases | |
| Overall BBPS (mean±SD): 7.1±1.3 | Overall BBPS: 6.2±1.1 | <0.001 | |
| Overall ADR: 49.8% | Overall ADR: 37.8% | 0.016 | |
| Cadoni et al. [7] | 408 cases | 408 cases | |
| Overall BBPS, median (IQR): 9.0 (7.0-9.0) | Overall BBPS: 8.0 (6.0-9.0) | <0.001 | |
| Right colon BBPS: 3.0 (2.0-3.0) | Right colon BBPS: 2.0 (2.0-3.0) | <0.001 | |
| Overall ADR: 49.3% | Overall ADR: 43.4% | 0.04 | |
| Right colon ADR: 24.0% | Right colon ADR: 16.9% | 0.03 | |
| Cheng et al. [18] | 86 cases | 86 cases (CO2 insufflation) | |
| Overall BBPS (mean±SD): 7.4±0.7 | Overall BBPS: 7.0±0.5 | <0.001 | |
| Overall ADR: 53.5% | Overall ADR: 58.1% | 0.645 | |
| Overall AMR*: 18.9% | Overall AMR: 28.2% | 0.071 | |
| Right colon AMR*: 17.5% | Right colon AMR: 33.8% | 0.034 |
*Miss rates are based on per adenoma analysis (number of adenomas missed in the first colonoscopy divided by the total number of adenomas detected during both the first and second colonoscopies). ADR: Adenoma detection rate, AMR: Adenoma miss rate, BBPS: Boston bowel preparation scale, SD: Standard deviation