Table 3.

Top 20 most abundant protein components of S. haematobium egg ESPs. The method of protein secretion as predicted by SecretomeP is listed; classically secreted (Y), non-classically secreted (A) or non-secreted (N). Proteins are ranked in order of the highest total unique matched peptides taken from three technical replicates.

Accession Number	Protein ID	# Unique Peptides	% Coverage	SecretomeP
A0A094ZWN9	Histone H4	11	61.5	N
A0A095B131	Polyubiquitin-C	8	30.2	N
A0A094ZDN2	Thioredoxin peroxidase 2	8	43.6	A
A0A095AIQ5	Cytochrome c	8	55.6	N
A0A095AKM1	Fructose-bisphosphate aldolase	8	27.4	N
A0A094ZX17	GLIPR1-like protein 1	7	39.6	Y
A0A095A2M4	Thioredoxin	7	61.6	A
A0A095ANZ3	Histone H3	5	33.3	A
A0A095A3Q8	Alpha-galactosidase	5	19.2	N
A5A6F5	14 kDa fatty acid-binding protein	5	32.3	A
A0A095A0L7	Superoxide dismutase [Cu-Zn]	4	37.5	A
A0A095A463	Uncharacterized protein	3	13.5	N
A0A095B4U1	Histone H2B	3	27.9	N
A0A094ZS57	16 kDa calcium-binding protein	3	25.2	A
A0A094ZZE3	Basement membrane proteoglycan	3	4.8	N
A0A095CF43	Alpha-galactosidase	3	12.5	A
A0A094ZS46	Spectrin alpha chain	3	1.0	N
A0A094ZVR4	Peptidase inhibitor 16	3	24.5	Y
A0A095CGL8	78 kDa glucose-regulated protein	3	6.8	Y
A0A094ZD40	Actin-2	2	13.8	A