Table 6.

Gene Ontology (GO) term annotations and their % representation for S. mansoni (Sm), S. japonicum (Sj) and S. haematobium (Sh) excreted/secreted products (ESPs) in our dataset compared with the complete NCBI protein groups. GO terms that are higher in ESP compared to NCBI groups are shaded

Molecular Function (MF)		Sm ESP	Sm NCBI	Sj ESP	Sj NCBI	Sh ESP	Sh NCBI
antioxidant activity	GO:0016209	2.68	0.86	3.91	0.61	6.98	0.22
binding	GO:0005488	46.34	52.08	50	46.9	56.98	55.97
catalytic activity	GO:0003824	47.32	35.86	40.63	37.47	31.4	36.28
molecular function regulator	GO:0098772	1.71	1.42	2.34	1.38	0	1.85
structural molecule activity	GO:0005198	0.98	1.62	1.56	7.76	1.16	2.1
transporter activity	GO:0005215	0.73	6.31	1.56	5.88	2.33	5.39
Biological Process (BP)
biological regulation	GO:0065007	5.11	10.03	8.05	6.87	10.33	11.35
carbon utilization	GO:0015976	1	0.12	0.77	0.26	0.33	0.11
cellular component organization	GO:0071840	1.56	4.18	3.45	6.95	4.67	4.51
cellular process	GO:0009987	37.67	35.07	39.46	35.06	31.67	34.69
detoxification	GO:0098754	0.89	0.3	1.15	0.22	1.67	0.1
developmental process	GO:0032502	2	1.11	0.77	0.96	3	1.15
immune system process	GO:0002376	0.33	0.16	0.38	0.31	0.67	0.14
localization	GO:0051179	2.22	7.35	1.92	9.73	3.67	7.05
metabolic process	GO:0008152	41.22	30.38	35.25	33.79	23.33	29.15
multicellular organismal process	GO:0032501	1.44	1.12	1.53	1.02	3.67	1.26
response to stimulus	GO:0050896	4.11	5.16	5.36	2.81	9.33	5.49
signalling	GO:0023052	0.67	3.58	1.15	1.6	3	4.32