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. 2021 Apr 21;7(17):eabf0344. doi: 10.1126/sciadv.abf0344

Fig. 1. PGS ice cube tray scaffold manufacturing process.

Fig. 1

(A) Schematic illustration of the ice cube tray PR scaffolds designed to have a reservoir layer for cell capture and retention and a through-hole layer for exchange of fluid, waste products, and nutrients both in vitro and during scaffold degradation in vivo. (B to G) Schematic illustration of the procedure to fabricate the ice cube tray PR scaffolds using a poly(glycerol sebacate) (PGS) prepolymer. (B) Through-hole and (C) reservoir etching processes of a Si master mold. (D) Molding and demolding processes of a hard-polydimethylsiloxane (h-PDMS) stamp from the Si master mold. (E) Mounting and demounting processes of the h-PDMS stamp for fabricating a PGS ice cube tray PR scaffold. (F) Delamination process of the scaffold using a razor blade. (G) Final PGS ice cube tray PR scaffold.