Table 2.
Clinical characteristics and laboratory examination of this SARS-CoV-2 RNA recurrent positive*
| Overall (n = 55) | Favipiravir (n = 36) | Control (n = 19) | P | |
|---|---|---|---|---|
| Clinical symptom | ||||
| Asymptom | 38 (69.1%) | 27 (75.0%) | 11 (57.9%) | 0.192 |
| Cough | 9 (16.4%) | 3 (8.3%) | 6 (31.6%) | 0.051 |
| Palpitation | 3 (5.5%) | 1 (2.8%) | 2 (10.5%) | 0.272 |
| Chest tightness | 3 (5.5%) | 1 (2.8%) | 2 (10.5%) | 0.272 |
| Diarrhea | 3 (5.5%) | 1 (2.8%) | 2 (10.5%) | 0.272 |
| Fever | 3 (5.5%) | 3 (8.3%) | 0 (0%) | 0.544 |
| Clinical type | >0.999 | |||
| Mild | 1 (1.8%) | 1 (2.8%) | 0 (0%) | |
| Moderate | 53 (96.4%) | 34 (94.4%) | 19 (100%) | |
| Severe | 1 (1.8%) | 1 (2.8%) | 0 (0%) | |
| Routine blood test | ||||
| WBC (10^9/L) Mean (SD) | 5.9 (1.6) | 5.9 (1.8) | 5.7 (1.4) | 0.648 |
| Neutrophil count (10^9/L) Mean (SD) | 3.5 (1.2) | 3.6 (1.3) | 3.4 (1.1) | 0.621 |
| Neutrophil percentage (%) Mean (SD) | 58.6 (7.3) | 58.8 (7.6) | 58.3 (6.9) | 0.832 |
| Lymphocyte count (10^9/L) Mean (SD) | 1.7 (0.4) | 1.7 (0.5) | 1.8 (0.4) | 0.746 |
| Lymphocyte percentage (%) Mean (SD) | 30.1 (7.2) | 29.6 (7.3) | 30.9 (7.0) | 0.553 |
| Monocyte count (10^9/L) Mean (SD) | 0.4 (0.2) | 0.4 (0.2) | 0.4 (0.1) | 0.226 |
| Monocyte percentage (%) Mean (SD) | 7.4 (2.7) | 7.7 (3.1) | 6.9 (1.4) | 0.311 |
| CRP (mg/L) Mean (SD) | 3.3 (7.6) | 4.0 (9.1) | 2.0 (2.8) | 0.350 |
| Blood biochemical test | ||||
| ALB (g/L) Mean (SD) | 43 (3.2) | 42.6 (3.2) | 44 (3.2) | 0.148 |
| TBIL (umol/L) Mean (SD) | 11.2 (5.1) | 11.7 (5.7) | 10 (3.2) | 0.249 |
| ALT (U/L) Mean (SD) | 28.6 (22.2) | 26.3 (21.7) | 33.6 (23) | 0.265 |
| AST (U/L) Mean (SD) | 21.9 (10.7) | 21.6 (11.3) | 22.5 (9.6) | 0.779 |
| LDH (U/L) Mean (SD) | 169.8 (35.7) | 166.3 (29.8) | 176.8 (45.7) | 0.324 |
| CK (U/L) Mean (SD) | 69.8 (36.1) | 71.8 (39.7) | 65.7 (28) | 0.582 |
| CK-MB (U/L) Mean (SD) | 11.4 (4.6) | 11 (4.2) | 12.1 (5.4) | 0.423 |
| ALP (U/L) Mean (SD) | 65 (24) | 63.9 (26.1) | 67.3 (19.2) | 0.639 |
| GGT (U/L) Mean (SD) | 36.4 (27.3) | 36.9 (28.2) | 35.2 (26) | 0.827 |
| Cr (umol/L) Mean (SD) | 61.3 (19.7) | 61.7 (21.7) | 60.4 (15.1) | 0.824 |
| UA (umol/L) Mean (SD) | 361.1 (130.1) | 370.6 (132.9) | 342.8 (126.6) | 0.493 |
NOTE: *The values shown are based on available data.
WBC white blood cell; SD standard deviation; ALB albumin; TBIL total bilirubin; ALT alanine aminotransferase; AST aspartate aminotransferase; LDH lactate dehydrogenase; CK creatine kinase; CK-MB creatine kinase; ALP alkaline phosphatase; GGT glutamyl transpeptidase; Cr creatinine; UA uric acid. One patient in the favipiravir group was chronic lymphocytic leukemia, with a lymphocyte percentage as high as 82.8%, so the patient was excluded from the analysis.