Table 3.
Dermoscopic Features of 56 cSCC by Histopathologic Diagnosis
| Characteristica | BD (n = 9) | Keratoacanthoma (n = 7) | Invasive cSCC (n = 40) | P |
|---|---|---|---|---|
| Vascular structures | ||||
| Dotted | 0 (0) | 0 (0) | 1 (2.5) | .82 |
| Hairpin-like | 0 (0) | 1 (14.3) | 2 (5.0) | .45 |
| Glomerular | 8 (88.9) | 1 (14.3) | 3 (7.5) | <.001 |
| Linear irregular | 1 (11.1) | 4 (57.1) | 24 (60.0) | .03 |
| Polymorphous | 0 (0) | 1 (14.3) | 10 (25.0) | .22 |
| Vascular arrangement | ||||
| Diffuse | 1 (11.1) | 1 (14.3) | 16 (40.0) | .14 |
| Clustered | 8 (88.9) | 1 (14.3) | 0 (0) | <.001 |
| Peripheral | 0 (0) | 5 (71.4) | 23 (57.5) | .004 |
| Features of keratinization | ||||
| Scales | 7 (77.8) | 4 (57.1) | 23 (57.5) | .52 |
| Keratin clods | 6 (66.7) | 3 (42.9) | 23 (57.5) | .63 |
| White circles | 5 (55.6) | 6 (85.7) | 28 (70.0) | .43 |
| Central keratin plug | 0 (0) | 4 (57.1) | 5 (12.5) | .004 |
| Erosions and ulcerations | ||||
| None | 0 (0) | 2 (28.6) | 4 (10.0) | .18 |
| Erosions | 5 (55.6) | 2 (28.6) | 4 (10.0) | .007 |
| Ulcerations | 4 (44.4) | 3 (42.9) | 32 (80.0) | .03 |
| Background color | ||||
| White | 1 (11.1) | 2 (28.6) | 1 (2.5) | .04 |
| Pink | 5 (55.6) | 1 (14.3) | 8 (20) | .07 |
| Red | 2 (22.2) | 1 (14.3) | 4 (10) | .60 |
| Pigmented | 1 (11.1) | 0 (0) | 1 (2.5) | .39 |
| Mixed | 0 (0) | 3 (42.9) | 26 (65) | .002 |
a
Values are n (%).
BD = Bowen disease; cSCC = cutaneous squamous cell carcinoma.