Table 4.
Associations between nine miRNAs differentially expressed and hr-HPV infection (FC ≤ 1.5, p < 0.05, and AUC ≥ 0.75).
| miRNAs | hr-HPV | p value∗ | ||
|---|---|---|---|---|
| Regulation | Negative | Positive | ||
| n (%) | n (%) | |||
| miR-205-5p | Upregulated | 7 (38.9%) | 11 (61.1%) | 0.095 |
| Downregulated | 1 (7.7%) | 12 (92.3%) | ||
|
| ||||
| miR-130a-3p | Upregulated | 7 (30.4%) | 16 (69.6%) | 0.642 |
| Downregulated | 1 (12.5%) | 7 (87.5%) | ||
|
| ||||
| miR-3136-5p | Upregulated | 4 (30.8%) | 9 (69.2%) | 0.689 |
| Downregulated | 4 (22.2%) | 14 (77.8%) | ||
|
| ||||
| miR-128-2-5p | Upregulated | 6 (35.3%) | 11 (64.7%) | 0.240 |
| Downregulated | 2 (14.3%) | 12 (8.7%) | ||
|
| ||||
| Let-7f-5p | Upregulated | 7 (33.3%) | 14 (66.7%) | 0.222 |
| Downregulated | 1 (10.0%) | 9 (90.0%) | ||
|
| ||||
| miR-202-3p | Upregulated | 7 (31.8%) | 15 (68.2%) | 0.379 |
| Downregulated | 1 (11.1%) | 8 (88.9%) | ||
|
| ||||
| miR-323a-5p | Upregulated | 8 (30.8%) | 18 (69.2%) | 0.291 |
| Downregulated | − | 5 (100.0%) | ||
|
| ||||
| miR-381-3p | Upregulated | 5 (20.8%) | 19 (79.2%) | 0.335 |
| Downregulated | 3 (42.9%) | 4 (57.1%) | ||
|
| ||||
| miR-4531 | Upregulated | 5 (21.7%) | 18 (78.3%) | 0.393 |
| Downregulated | 3 (37.5%) | 5 (62.5%) | ||
∗Chi-square test was used to identify associations between miRNA expression and hr-HPV infection.