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Id4 regulated the migration, invasion, and metastatic potentials of CRC cells. (a) Wound healing assay of CRC cells. (b) Migration assay of CRC cells (Boyden chamber assay). (c) Invasion assay of CRC cells (Boyden chamber assay). (d) Intrasplenic implantation of HCT116-Id4 cells or control cells. The number of tumors in the spleens and liver metastases of the HCT116-Id4 group decreased significantly.
