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. 2020 Oct 13;25(5):2959–2968. doi: 10.1007/s00784-020-03616-7

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© The Author(s) 2020

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Fig. 3 — Representative bone defect treated with DBBM/GTR (control group). (a) Baseline clinical view, lower left molar (36) presenting with a pre-operative probing depth (PD) of 9 mm. (b) Surgical view after flap elevation and granulation tissue removal, presenting with a intraoperative probing of the defect INTRA DD = 5 mm. (c) Surgical view of the lingual aspect of the bony defect. (d) Intrasurgical view of the defect filled with Cerabone® (botiss, biomaterials GmbH, Zossen, Germany) and covered with trimmed collagen membrane (Collprotect®, botiss, biomaterials GmbH, Zossen, Germany). (e) Clinical view 1 year after treatment; a post-operative probing depth (PD) of 4 mm. (f, g) One year post-op minimally invasive reentry; complete filling of the defect with bonelike tissue. (h) Reentry; probing of the residual defect INTRA DD = 3 mm (after granulation tissue removal). (i) Baseline radiographic aspect of intrabony defect mesially to the lower left first molar. (j) Radiographic result 1 year after treatment