Table 5.
DKK3: Prevalent and new-onset CKD.
| Prevalent CKD | New-onset CKD | |||||
|---|---|---|---|---|---|---|
| Cases, n (%) | Odds ratio (95% CI) | P-value | Cases, n (%) | Hazard ratio (95% CI) | P-value | |
| DKK3† | 1361 (17.2) | 1.84 (1.59–2.13) | < 0.001 | 951 (17.1) | 1.45 (1.25–1.69) | <0.001 |
| DKK3†, age | 1361 (17.2) | 1.06 (0.90–1.25) | 0.472 | 951 (17.1) | 0.91 (0.76–1.09) | 0.306 |
| DKK3†, age, sex | N.A | N.A | N.A | N.A | N.A | N.A |
| DKK3†, models | ||||||
| Multivariable model | N.A | N.A | N.A | N.A | N.A | N.A |
| Clinical model | N.A | N.A | N.A | N.A | N.A | N.A |
CI Confidence Interval, CKD Chronic kidney disease, DKK3 Dickkopf-3. Multivariable model as presented in Table 3. Clinical model includes age, sex, body mass index, systolic blood pressure, glucose† and cholesterol. Prevalent CKD: N = 7946. New onset CKD: N = 5548. †Log2-transformed.