Table 2.

Quantification of the transduction pattern after intra-nerve injection of AAV2/9 and AAV2/rh10-CAG-GFP in rodents.

	Transduction rate after intra-nerve injection (%)
	AAV2/9-CAG-GFP				AAV2/rh10-CAG-GFP
	Mouse		Rat		Mouse	Rat
	Adult	Pup	Adult	Pup	Adult	Pup
Proximally	63 ± 24	74 ± 7	NA	81 ± 7	42 ± 22	53 ± 3
Injection site	93 ± 2	85 ± 15	80 ± 14	87 ± 1	51 ± 11	46 ± 5
Distally	91 ± 2	74 ± 14	NA	50 ± 24	42 ± 16	5 ± 6

Animal groups were composed of three animals. Mouse and rat pups were injected at P2-P3 and P6-P7 respectively. Adult mice and rats were injected at 2-3 months old. All animals were sacrificed one month post-injection. The transduction rate is the percentage of transduced mSC (GFP and MBP positive cells surrounding Tuj1 positive axons) on the overall number of mSC (MBP positive cells surrounding Tuj1 positive axons) per section. Proximal distances of the injection site were 2 cm for mice and 3 cm for rats. Distal distances of the injection site were 0.5 cm for mice and 1 cm for rats. The results are expressed as the mean ± SD. NA, Not available (not done). Source data are provided as a Source Data file.