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. 2021 Apr 21;11:8584. doi: 10.1038/s41598-021-88017-w

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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In vivo ultrasound and dilation change. (a) Representative B-mode in vivo ultrasound images of abdominal aortas before pump implantation, at 4 weeks when the infusion of Ang II was finished and treatment started, and 8 weeks when the animals were euthanized; (b) Gross view of representative aortas from BLN-NPs (b1), PGG-NPs (b2) and control groups (b3) at 8 week; (c) Dilation percentage of BLN-NPs group, PGG-NPs group and control group. After therapy PGG-NPs group showed progressive reversal of aneurysmal dilation while control and BLN-NPs groups showed continuous increase in aneurysms. *Indicate timepoint that have dilation percentage significantly different from week 4 (p < 0.1); bars indicate significant difference between groups (p < 0.05).