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. 2021 Apr 21;4:490. doi: 10.1038/s42003-021-02003-6

Fig. 1. Upregulation of β3 integrin in lung adenocarcinoma is associated with poor survival.

Fig. 1

a Representative immunohistochemistry images of β3 integrin expression in human normal lung and lung adenocarcinoma tumor tissues. Scale bar, 50 µm. b β3 integrin expression in human normal lung tissues (n = 52) versus lung adenocarcinoma tumor tissues (n = 112). The staining intensity was graded as follows: − (negative), + (weak), ++ (moderate), and +++ (strong). The source data are provided in Supplementary Data 1. c Kaplan-Meier analysis of the correlation between β3 integrin expression and overall survival for lung adenocarcinoma patients (n = 720) using the database Kaplan-Meier Plotter. P values were calculated using a log-rank test.